Funded Research Projects

2015

Determining the temporal, spatial and molecular signature of hypoxia in spinal muscular atrophy

Principal investigator(s):

Professor Simon Parson

2015

The ROCK-ERK signalling network in SMA - mediator of neurodegeneration and SMN independent treatment target

Principal investigator(s):

Dr. Niko Hensel

2015

The regulation of SMN function in SMA

Principal investigator(s):

Dr. Olga Tapia,

2014

A Spinal Muscular Atrophy Drosophila Model for In Vivo Drug Discovery

Principal investigator(s):

Dr. Ruben Artero

2014

Identification of microRNAs as biomarkers and potential therapeutic targets in spinal muscular atrophy

Principal investigator(s):

Professor Francesco Muntoni

2014

Study of the role of SMN in the regulation of muscle-resident progenitors for the identification of novel therapeutic targets for SMA

Principal investigator(s):

Dr. Martine Barkats

2013

Cellular basis of motor circuit dysfunction induced by SMN deficiency

Principal investigator(s):

Dr. George Mentis

2013

Modulating SMN2 splicing with dual inhibitors of Sam68 and hnRNP A1: A novel therapeutic approach for Spinal Muscular Atrophy

Principal investigator(s):

Professor Eduardo Tizzano