Funded Research Projects

2017

Combinatorial ASO therapy using SMN-dependent and SMN-independent protection against SMA

Principal investigator(s):

Dr. Laura Torres-Benito

2017

Defining the role of the motor axon translatome in SMA pathogenesis

Principal investigator(s):

Professor Tom Gillingwater

2017

Restoring Disturbed Energy Homeostasis in SMA motor neurons

Principal investigator(s):

Dr. Min Jeong Kye

2016

Determining the temporal, spatial and molecular signature of hypoxia in SMA

Principal investigator(s):

Professor Simon Parson

2016

The ROCK-ERK signalling network in SMA - mediator of neurodegeneration and SMN independent treatment target

Principal investigator(s):

Dr. Niko Hensel

2016

The regulation of SMN function in SMA

Principal investigator(s):

Dr. Olga Tapia,

2015

A Spinal Muscular Atrophy Drosophila Model for In Vivo Drug Discovery

Principal investigator(s):

Dr. Reuben Artero

2015

Identification of microRNAs as biomarkers and potential therapeutic targets in spinal muscular atrophy

Principal investigator(s):

Professor Francesco Muntoni